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Engineering Biomedical Information: From Bioinformatics to Biosurveillance >> Content Detail



Lecture Notes



Lecture Notes

Lec #TOPICS
1Introduction: Brief Introduction to Biomedical Informatics and Outline of the Course - Dr. M. F. Ramoni (PDF)
2Bioinformatics: Introduction to the Bioinformatics Module. Central Dogma of Molecular Biology. Short Biology Primer. Human Genome Project. The Role of Computational Sciences in the New Biology - Dr. M. F. Ramoni (PDF)
3Structural Genomics: Human Variations. Genetic and Genomic Studies. Evolutionary Pressure and Selection. SNPs and Haplotypes. Haplotype-tagging - Dr. M. F. Ramoni (PDF)
4Human Variations: Human Variations. Analysis of Human Variations. Association Studies. Complex Traits. The Genomic Study of the Future - Dr. M. F. Ramoni (PDF)
5Sequencing: Genome Sequencing at the Human Genome Project - Dr. R. Nicol
6Genome-wide Genomic: SNP Microarrays and High-density Genotyping - Dr. S. Monti
7Functional Genomics - Dr. A. Kho (PDF) Courtesy of Dr. Alvin Kho. Used with permission.
8Expression Microarrays: Meta Elements of Transcriptome Profiling - Dr. A. Kho (PDF - 3.6 MB) Courtesy of Dr. Alvin Kho. Used with permission.
9Annotation Databases: This Lecture will Present the Most Important Public Databases of Genomic Knowledge Currently Available. Using the Flow of Information Inside a Cell (DNA - RNA - Proteins) as our Guiding Principle, We will Highlight the Specific Features and Characteristics of Each Resource, their Limitations, and How they Relate to Each Other - Dr. A. Riva
10Genomic Privacy - Dr. C. Cassa
11Pharmacogenomics - Dr. S. Weiss
12Proteomics: Introduction to the Proteomics Module. Old Proteomics: Western Blot, SDS-PAGE, etc. New Proteomics: Automation/parallel High-throughput Analysis with Mass Spectrometry (SELDI, MS/MS), Yeast Two-hybrid, and Protein Microarrays - Dr. G. Alterovitz
13Proteomics: Interactome: Introduction to the biological networks with focus on interactomes. Common themes and fundamental algorithm considerations underlying networks are explored with interactome examples such as the human massome network. Different types of biological networks are outlined as well as corresponding mathematical representations and related analysis. Recent developments in scale-free networks and analysis are described - Dr. G. Alterovitz
14Clinical Informatics: Computing Support for the Academic Healthcare Enterprise - Dr. D. Nigrin
15Telemedicine - Dr. H. Fraser
16Decision Support Systems: Introduction to Decision Support Systems and Artificial Intelligence Applications in Biomedical Sciences - Dr. M. F. Ramoni (PDF)
17Patient Confidentiality: Slightly Controlled Information Exhibitionism in the Genetic Age - Dr. I. S. Kohane (PDF - 1.2 MB)
18Revision Class - Dr. M. F. Ramoni
19Geographic Health Information: Slightly Controlled Information Exhibitionism in the Genetic Age - Dr. J. Brownstein
20Medical Image Processing: Image Guided Therapy and the National Alliance for Medical Image Computing - Dr. R. Kikinis
21Biosurveillance - Dr. K. Mandl
22Pharmacoeconomics - Dr. S. Finkelstein
23Public Health Informatics - Dr. B. Reis
24Student Presentations
25Student Presentations (cont.)

 








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