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Ubiquitination: The Proteasome and Human Disease >> Content Detail



Lecture Notes



Lecture Notes

LEC #         TOPICS                                             
1Introduction (PDF)
2Discovery of the Ubiquitin Conjugation System (PDF)
3Protein Degradation in Trafficking Membranes I: Endoplasmic Reticulum Associated Degradation (ERAD) Pathway (PDF)
4Protein Degradation in Trafficking Membranes II: Endocytosis and lysosomal Degradation (PDF)
5Role of Ubiquitination in Transcriptional Regulation (PDF)
6Role of Ubiquitination in Cell Cycle Control and Programmed Cell Death (PDF)
7Ubiquitin-like Proteins (PDF)
8Functions of the Ubiquitin-Proteasome System in the Immune System (PDF)
9Ubiquitin and Cancer (PDF)
10Ubiquitin and Neurodegenerative Diseases: Alzheimer's and Parkinson's Diseases (PDF)
11More Diseases Involving Ubiquitin: Huntington's and Von Hippel-Lindau Disease (PDF)
12Too Much Degradation Can Be as Bad as Not Enough: Cystic Fibrosis and Liddle's Syndrome (PDF)
13Potential Therapeutic Strategies in Ubiquitin-Related Diseases (PDF)
14Oral Presentations

Final Comments and Course Evaluation

 








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