| SES # | TOPICS | READINGS |
|---|---|---|
| 1 | Introduction | |
| 2 | Scientific reading, writing and learning mechanisms of simple invertebrates | Dudai, Y., Y. N. Jan, D. Byers, W. G. Quinn, and S. Benzer. "Dunce, a Mutant of Drosophila Deficient in Learning." Proc Natl Acad Sci USA 73 (1976): 1684-1688. Carew, T. J., E. T. Walters, and E. R. Kandel. "Classical Conditioning in a Simple Withdrawal Reflex." In Aplysia Californica J Neurosci 1 (1981): 1426-1437. |
| 3 | Synaptic plasticity in rodent hippocampal slices | Schwartzkroin, P. A., and K. Wester. "Long-lasting Facilitation of a Synaptic Potential Following Tetanization in the in vitro Hippocampal Slice." Brain Res 89 (1975): 107-119. Stanton, P. K., and J. M. Sarvey. "Blockade of Long-term Potentiation in Rat Hippocampal CA1 Region by Inhibitors of Protein Synthesis." J Neurosci 4 (1984): 3080-3088. |
| 4 | Molecular mechanisms underlying LTP | Coan, E. J., W. Saywood, and G. L. Collingridge. "MK-801 Blocks NMDA Receptor-mediated Synaptic Transmission and Long Term Potentiation in Rat Hippocampal Slices." Neurosci Lett 80 (1987): 111-114. Hayashi, Y., S. H. Shi, J. A. Esteban, A. Piccini, J. C. Poncer, and R. Malinow. "Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction." Science 287 (2000): 2262-2267. |
| 5 | Complicating the model of LTP | Dudek, S. M., and M. F. Bear. "Bidirectional Long-term Modification of Synaptic Effectiveness in the Adult and Immature Hippocampus." J Neurosci 13 (1993): 2910-2918. Borroni, A. M., H. Fichtenholtz, B. L. Woodside, and T. J. Teyler. "Role of Voltage-dependent Calcium Channel Long-term Potentiation (LTP) and NMDA LTP in Spatial Memory." J Neurosci 20 (2000): 9272-9276. |
| 6 | The Morris water maze | Morris, R. "Developments of a Water-maze Procedure for Studying Spatial Learning in the Rat." J Neurosci Methods 11 (1984): 47-60. Halagappa, V. K., Z. Guo, M. Pearson, Y. Matsuoka, R. G. Cutler, F. M. Laferla, and M. P. Mattson. "Intermittent Fasting and Caloric Restriction Ameliorate Age-related Behavioral Deficits in the Triple-transgenic Mouse Model of Alzheimer's Disease." Neurobiol Dis 26 (2007): 212-220. |
| 7 | Place cells | O'Keefe, J., and J. Dostrovsky. "The Hippocampus as a Spatial Map. Preliminary Evidence from Unit Activity in the Freely-moving Rat." Brain Res 34 (1971): 171-175. Ji, D., and M. A. Wilson. "Coordinated Memory Replay in the Visual Cortex and Hippocampus During Sleep." Nat Neurosci 10 (2007): 100-107. |
| 8 | Field trip | |
| 9 | NMDA receptors and place cells | Tsien, J. Z., P. T. Huerta, and S. Tonegawa. "The Essential Role of Hippocampal CA1 NMDA Receptor-dependent Synaptic Plasticity in Spatial Memory." Cell 87 (1996): 1327-1338. McHugh, T. J., K. I. Blum, J. Z. Tsien, S. Tonegawa, and M. A. Wilson. "Impaired Hippocampal Representation of Space in CA1-specific NMDAR1 Knockout Mice." Cell 87 (1996): 1339-1349. |
| 10 | Hippocampal representation of space in contextual fear conditioning | Wiltgen, B. J., M. J. Sanders, S. G. Anagnostaras, J. R. Sage, and M. S. Fanselow. "Context Fear Learning in the Absence of the Hippocampus." J Neurosci 26 (2006): 5484-5491. Moita, M. A., S. Rosis, Y, Zhou, J. E. LeDoux, and H. T. Blair. "Putting Fear in its Place: Remapping of Hippocampal Place Cells During Fear Conditioning." J Neurosci 24 (2004): 7015-7023. |
| 11 | Synaptic tagging | Sajikumar, S., S. Navakkode, and J. U. Frey. "Identification of Compartment- and Process-specific Molecules Required for "Synaptic Tagging" During Long-term Potentiation and Long-term Depression in Hippocampal CA1." J Neurosci 27 (2007): 5068-5080. Kauderer, B. S., and E. R. Kandel. "Capture of a Protein Synthesis-dependent Component of Long-term Depression." Proc Natl Acad Sci USA 97 (2000): 13342-13347. |
| 12 | Other aspects of place cells | Oler, J. A., and E. J. Markus. "Age-related Deficits in the Ability to Encode Contextual Change: A Place Cell Analysis." Hippocampus 10 (2000): 338-350. Hafting, T., M. Fyhn, S. Molden, M. B. Moser, and E. I. Moser. "Microstructure of a Spatial Map in the Entorhinal Cortex." Nature 436 (2005): 801-806. |
| 13 | Does LTP really happen in the brain? | Whitlock, J. R., A. J. Heynen, M. G. Shuler, and M. F. Bear. "Learning Induces Long-term Potentiation in the Hippocampus." Science 313 (2006): 1093-1097. Barnes, C. A., M. W. Jung, B. L. McNaughton, D. L. Korol, K. Andreasson, and P. F.Worley. "LTP Saturation and Spatial Learning Disruption: Effects of Task Variables and Saturation Levels." J Neurosci 14 (1994): 5793-5806. |
| 14 | Schemas' of memory | Kim, J. J., and M. S. Fanselow. "Modality-specific Retrograde Amnesia of Fear." Science 256 (1992): 675-677. Tse, D., R. F. Langston, M. Kakeyama, I. Bethus, P. A. Spooner, E. R. Wood, M. P. Witter, and R. G. Morris. "Schemas and Memory Consolidation." Science 316 (2007): 76-82. |