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Course Info

  • Course Number / Code:
  • HST.535 (Fall 2004) 
  • Course Title:
  • Principles and Practice of Tissue Engineering 
  • Course Level:
  • Graduate 
  • Offered by :
  • Massachusetts Institute of Technology (MIT)
    Massachusetts, United States  
  • Department:
  • Health Sciences and Technology 
  • Course Instructor(s):
  • Prof. Myron Spector
    Prof. Fu-Zhai Cui 
  • Course Introduction:
  •  


  • HST.535 Principles and Practice of Tissue Engineering



    Fall 2004




    Course Highlights


    This course features a complete set of lecture slides.


    Course Description


    The principles and practice of tissue engineering (and regenerative medicine) are taught by faculty of the Harvard-MIT Division of Health Sciences and Technology (HST) and Tsinghua University, Beijing, China. The principles underlying strategies for employing selected cells, biomaterial scaffolds, soluble regulators or their genes, and mechanical loading and culture conditions, for the regeneration of tissues and organs in vitro and in vivo are addressed. Differentiated cell types and stem cells are compared and contrasted for this application, as are natural and synthetic scaffolds. Methodology for the preparation of cells and scaffolds in practice is described. The rationale for employing selected growth factors is covered and the techniques for incorporating their genes into the scaffolds are examined. Discussion also addresses the influence of environmental factors including mechanical loading and culture conditions (e.g., static versus dynamic). Methods for fabricating tissue-engineered products and devices for implantation are taught. Examples of tissue engineering-based procedures currently employed clinically are analyzed as case studies.

    Archived webcast lecture videos for the Fall 2008 version of this class can be found at the HST.535 Fall 2008 website.



    Technical Requirements


    Microsoft® Powerpoint® software is recommended for viewing the .ppt files found on this course site. Free Microsoft® Powerpoint® viewer software can also be used to view the .ppt files.

     

ACKNOWLEDGEMENT:
This course content is a redistribution of MIT Open Courses. Access to the course materials is free to all users.






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